PEG MGF
PEG MGF (pegylated mechano growth factor) is a synthetic E-domain peptide derived from the mechano-sensitive IGF-1 splice variant (MGF), modified by PEGylation at a lysine residue. The polyethylene glycol conjugation attenuates proteolytic degradation and renal clearance, shifting pharmacokinetic half-life substantially beyond the unmodified MGF sequence in biochemical assays. In myoblast and satellite cell culture the E-domain engages intracellular signaling distinct from canonical IGF-1R-mediated IGF-1 activity — making PEG MGF the tool of choice when MGF-specific pathway contributions need to be resolved from bulk IGF-1 signaling. For laboratory research use only.
- CAS
- 108174-48-7
- MW
- 2867.2 g/mol (core peptide; varies with PEG chain)
- Formula
- C121H200N42O39
- Purity
- >=98.9 HPLC
- Storage
- -20 °C, lyophilized
What is PEG MGF?
PEG MGF is a synthetic research compound studied in laboratory settings. It has molecular formula C121H200N42O39, a molecular weight of 2867.2 g/mol (core peptide; varies with PEG chain), CAS 108174-48-7. It is intended for in vitro research use only and is not for human or animal use.
What purity is AminoZone's PEG MGF?
AminoZone supplies PEG MGF at >=98.9% purity, verified by third-party HPLC analysis. A certificate of analysis is available on request.
How is PEG MGF supplied?
PEG MGF is supplied as a lyophilized powder in sealed research-grade vials, stored -20 °C, lyophilized, intended for in vitro and laboratory research use only.