MOTS-c
MOTS-c is a 16-amino acid peptide encoded in the 12S rRNA region of the mitochondrial genome, distinguishing it as the first mitochondrial-derived peptide (MDP) with characterized systemic metabolic signaling capacity. In skeletal muscle and adipocyte culture systems it activates AMPK, drives FGF21 upregulation, and potentiates insulin-independent glucose uptake. The mitochondrial coding origin is the key specification: it positions MOTS-c as the canonical probe for studying retrograde mito-nuclear communication and the mechanisms governing metabolic homeostasis signaling. For laboratory research use only.
- CAS
- 1627580-64-6
- MW
- 2174.59 g/mol
- Formula
- C100H152N28O22S2
- Purity
- >=99.3 HPLC
- Storage
- -20 °C, lyophilized
What is MOTS-c?
MOTS-c is a synthetic research compound studied in laboratory settings. It has molecular formula C100H152N28O22S2, a molecular weight of 2174.59 g/mol, CAS 1627580-64-6. It is intended for in vitro research use only and is not for human or animal use.
What purity is AminoZone's MOTS-c?
AminoZone supplies MOTS-c at >=99.3% purity, verified by third-party HPLC analysis. A certificate of analysis is available on request.
How is MOTS-c supplied?
MOTS-c is supplied as a lyophilized powder in sealed research-grade vials, stored -20 °C, lyophilized, intended for in vitro and laboratory research use only.