GLP-1(S)
GLP-1(S) (Semaglutide) is a synthetic GLP-1 receptor agonist carrying 94% sequence homology to native GLP-1 7-36 amide, with two key engineering decisions: an Aib substitution at position 8 that eliminates DPP-IV recognition, and a C18 fatty di-acid chain at Lys26 that drives reversible albumin binding. Together these modifications shift plasma half-life well beyond native GLP-1 in pharmacokinetic models — the property that makes it the preferred scaffold for long-acting GLP-1R agonism research, receptor internalization kinetics, and beta-cell cAMP dose-response assays. For laboratory research use only.
- CAS
- 910463-68-2
- MW
- 4113.58 g/mol
- Formula
- C187H291N45O59
- Purity
- >=99.0 HPLC
- Storage
- -20 °C, lyophilized
What is GLP-1(S)?
GLP-1(S) is a synthetic research compound studied in laboratory settings. It has molecular formula C187H291N45O59, a molecular weight of 4113.58 g/mol, CAS 910463-68-2. It is intended for in vitro research use only and is not for human or animal use.
What purity is AminoZone's GLP-1(S)?
AminoZone supplies GLP-1(S) at >=99.0% purity, verified by third-party HPLC analysis. A certificate of analysis is available on request.
How is GLP-1(S) supplied?
GLP-1(S) is supplied as a lyophilized powder in sealed research-grade vials, stored -20 °C, lyophilized, intended for in vitro and laboratory research use only.